Whole Body Cryotherapy (WBC) is an advanced technology that applies very cold temperatures, by way of nitrogen vapor, to the body for relief of chronic inflammation, pain and soreness. This modality was first utilized in Japan in the early 1970s by Dr. Yamaguchi to treat rheumatoid arthritis. Studies conducted over the last few decades have established WBC as a powerful treatment for inflammatory disorders and injuries. Temperatures inside the chamber on average dip as low as 250ºF below zero, temporarily lowering the surface temperature of the skin and stimulating the body’s regulatory response.
WBC from review of various studies and sources shows two very prominent systemic responses. “Cold Shock” – dropping the skin temperature on a whole body level and primarily around the core where the concentration of thermo-receptive (nerve ending neurons) are located send distress signals to the brain. The reactivity in the brain is two-fold. First, there is a Central Nervous System (CNS) reaction whereby the hypothalamus directs the endocrine system to release endorphins in vast amounts quickly. Additionally, cold shock protein (norepinephrine) is released in the brain. Norepinephrine is a powerful anti-inflammatory protein which inhibits TNF-α
production (an inflammatory cytokine produced by the immune system in response to injury, foreign bodies, etc.) Endorphins are the feel good hormone, elevating mood, an opioid-like response, blocking pain reception signals. This CNS response is the Symptomatic reaction we get with whole body cryotherapy to pain and inflammation. Patients experience improved range of motion with pain reduction almost immediately.
Additionally, the brain senses rapid heat transfer (hypothermic simulation) due to extreme skin temperature change, thus creating a parasympathetic (Autonomic Nervous System) reaction with circulation. Blood draws from the extremities to the core to protect from heat transfer. This occurs within 30-seconds to one minute of exposure. Blood pooling in the core oxygenates and is enriched with nutrients. Upon exit of the chamber, as the skin temperature rapidly rewarms, the brain releases the blood supply back to the extremities with a vasodilation estimated to be 3:1. Ironically, over the short duration exposure, there is little change in core temp. This process flushes areas of injury of toxic waste and bad cells replenishing with good blood to stimulate cellular regeneration. This is the systemic circulation benefit dealing with underlying condition.
This process should not be thought of as comparable to ice or immersion. It does not have a gradual metabolic effect, it has a rapid thermogenic and peripheral effect with the added chemical release mentioned above
The body can be amazing in healing itself. However, with whole body inflammation and chronic conditions, sometimes efficiencies break down. To accelerate recoveries, sympathetic stimulation (implied stress – cold shock) can reset the system while producing excess amounts of very functional and productive hormones and proteins to do their jobs. The effects are multiplied when the body is circulating at a highly productive level with full transport and delivery to all extremities.
Cryotherapy Provides Benefits in Three Primary Settings